COMPOSITION

Each tablet contains...

Lactobacillus paracasei GMNL-33 .................. NLT 1 billion Cells

Cichorium intybus root powder .................. 50 mg

MECHANISM OF ACTION

1
Anti-pathogenic activity:
  • Heat-killed L. paracasei GMNL-33 inhibits the periodontal pathogens including Porphyromonas gingivalis, Prevotella intermedia, Centipeda periodont and Dental plaque sample collected from teeth with periodontal disease
  • Heat-killed L. paracasei GMNL-33 also inhibits growth of dental caries pathogen S. mutans
2
Anti-adhesive:

Heat-killed L. paracasei GMNL-33 inhibits adhesion of S. mutans to gingival cavity, also significantly inhibit the biofilm formation of S. mutans.

3
Coaggregation and agglutination:

Coaggregate to oral pathogens including S. mutans, P. gingivalis, Fusobacterium nucleatum and Actinobacillus actinomycetemcomitans for its removal.

4
Heat-killed L. paracasei GMNL-33 restores oral microflora
5
Immunomodulatory activity:

Heat-killed L. paracasei increases salivary IgA levels.

KEY CHARACTERISTICS

1
Targeted Action:

Heat-killed L. paracasei GMNL-33 specifically inhibits caries-causing bacteria (e.g., Streptococcus mutans) without harming beneficial microbiota, supporting oral microbial balance.

2
Biofilm Disruption:

Heat-killed L. paracasei GMNL-33 effectively reduces dental plaque formation by disrupting biofilm integrity, a significant challenge for antibiotics.

3
Anti-Inflammatory Benefits:

Heat-killed L. paracasei GMNL-33 reduces gingival inflammation by modulating immune responses, providing dual benefits of antimicrobial and anti-inflammatory effects.

4
No Risk of Resistance:

Unlike antibiotics, Heat-killed L. paracasei GMNL-33 do not contribute to antimicrobial resistance, making them a sustainable alternative.

5
Enhanced Oral Health:

By promoting a balanced oral microbiome, heat-killed L. paracasei GMNL-33 help in long-term maintenance of oral health, reducing the likelihood of recurrent infections.

ADVANTAGES

Advantages of L. paracasei GMNL-33:

While antibiotics are reactive, heat-killed probiotics like L. paracasei GMNL-33 focus on preventing infections by strengthening the oral ecosystem.

1

Safety Profile: Heat-killed L. paracasei GMNL-33 are naturally derived and exhibit excellent safety and tolerability, even with prolonged use.

2

Holistic Benefits: In addition to addressing oral infections, heat-killed L. paracasei GMNL-33 contribute to overall systemic health through their positive effects on inflammation and immunity.

FEATURES

Key Features of L. paracasei GMNL-33
1

Inhibits caries-causing bacteria Streptococcus mutans, periodontal pathogens (Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans)

2

Reduces dental plaque formation

3

Reduces gingival inflammation

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